Fig. 1 · Structure
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USP7-IN-8
USP7 Inhibitor
USP7-IN-8 is a selective inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 1.4 μM demonstrated in an Ub-Rho110 assay. This compound exhibits specificity, showing no activity against USP47 and USP5. USP7-IN-8 has been associated with anticancer effects, making it a valuable tool for research into cancer biology and therapeutic strategies targeting the ubiquitin-proteasome system.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2009273-60-1 |
| Applications | USP7 Inhibitor |
| Formula | C21H21N3O2 |
| Molecular Weight | 347.41 |
| SMILES | O=C(NC)C1=CC=C(C2=C(CC)C(C3=CC=C(O)C=C3)=C(N)N=C2)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.