Fig. 1 · Structure
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USP7/USP47 inhibitor 1
USP47 Inhibitor
USP7/USP47 inhibitor 1 is a selective inhibitor of USP47, demonstrating an EC50 of 14 μM for this target, while exhibiting an EC50 of greater than 31.6 μM for USP7. This compound is valuable for investigating the biological roles of USP47 in cancer research, enabling the exploration of potential therapeutic strategies targeting deubiquitinating enzymes. Its specificity may facilitate studies aimed at delineating the contributions of USP47 in oncogenic processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 90680-28-7 |
| Applications | USP47 Inhibitor |
| Formula | C12H9NO3S2 |
| Molecular Weight | 279.33 |
| SMILES | CC(C1=CC([N+]([O-])=O)=C(SC2=CC=CC=C2)S1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.