Fig. 1 · Structure
Documents & Downloads
USP8-IN-1
USP8 Inhibitor
USP8-IN-1 is a selective inhibitor of the USP8 enzyme, exhibiting an IC50 value of 1.9 μM. This compound demonstrates significant anti-proliferative activity in H1975 cancer cells, with a GI50 of 82.04 μM. USP8-IN-1 is utilized in research focused on cancer biology, particularly in studies investigating the role of deubiquitinating enzymes in tumor growth and progression.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2477650-96-5 |
| Applications | USP8 Inhibitor |
| Formula | C18H21N5O3S |
| Molecular Weight | 387.46 |
| SMILES | [O-][N+](C1=CC=C(NC(N2CCN(CC2)C3=CC=C(C=C3N)OC)=S)C=C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.