UV Cleavable Biotin-PEG2-Azide is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing molecules and can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. Its UV-cleavable properties make it particularly useful for studying protein interactions and degradation pathways in cellular contexts.
UV Cleavable Biotin-PEG2-Azide is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-bearing molecules and can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. Its UV-cleavable properties make it particularly useful for studying protein interactions and degradation pathways in cellular contexts.
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