Fig. 1 · Structure
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Valacyclovir hydrochloride
Antiviral Agent
Valacyclovir hydrochloride is an orally active antiviral agent targeting herpes simplex virus, herpes zoster, and herpes B. It exerts its effects by inhibiting viral DNA synthesis, demonstrating a half maximal inhibitory concentration (IC50) of 2.9 μg/ml against HSV-1. This compound serves as a prodrug of acyclovir, enhancing its bioavailability for therapeutic use in herpes virus infections. Valacyclovir hydrochloride is utilized in research applications aimed at understanding and developing treatments for viral infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 124832-27-5 |
| Applications | Antiviral Agent |
| Formula | C13H21ClN6O4 |
| Molecular Weight | 360.80 |
| Synonyms | Valaciclovir hydrochloride |
| SMILES | N[C@@H](C(C)C)C(OCCOCN1C=NC2=C1N=C(N)NC2=O)=O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.