Valdecoxib-d3 is a deuterium-labeled derivative of Valdecoxib, a highly selective and potent inhibitor of cyclooxygenase-2 (COX-2), exhibiting an IC50 of 5 nM against COX-2 and significantly less activity at 140 μM for COX-1. This stable isotope can be utilized in pharmacokinetic studies, offering insights into the metabolic pathways and biological effects of COX-2 inhibition. Valdecoxib-d3 is particularly useful in research related to inflammatory conditions, such as arthritis and pain management.
Valdecoxib-d3 is a deuterium-labeled derivative of Valdecoxib, a highly selective and potent inhibitor of cyclooxygenase-2 (COX-2), exhibiting an IC50 of 5 nM against COX-2 and significantly less activity at 140 μM for COX-1. This stable isotope can be utilized in pharmacokinetic studies, offering insights into the metabolic pathways and biological effects of COX-2 inhibition. Valdecoxib-d3 is particularly useful in research related to inflammatory conditions, such as arthritis and pain management.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
