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Vanoxonin

Thymidylate Synthase Inhibitor

Vanoxonin is a potent inhibitor of thymidylate synthase derived from Saccharopolyspora hirsuta, exhibiting an IC50 value of 0.7 μg/mL. This compound plays a crucial role in research applications focused on cancer therapeutics, particularly in the development of antimetabolites that target DNA synthesis. By disrupting thymidylate production, Vanoxonin may hinder cell proliferation in rapidly dividing cancer cells.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	86933-99-5
Applications	Thymidylate Synthase Inhibitor
Formula	C₁₈H₂₅N₃O₉
Molecular Weight	427.41
SMILES	O=C([C@@H](NC([C@@H](NC(C1=CC=CC(O)=C1O)=O)[C@@H](C)O)=O)CCCN(O)C(C)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.