Fig. 1 · Structure

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Vapiprost

Thromboxane A2 Receptor Antagonist

Vapiprost is a thromboxane A2 receptor (TXA2 receptor) antagonist that effectively inhibits thromboxane-mediated platelet aggregation and ATP release. It demonstrates a potent inhibitory effect on the aggregation induced by U-46619, collagen, or arachidonic acid (AA) with an IC50 of less than 2.1×10^-8 M. Vapiprost is utilized in research applications focused on cardiovascular studies and platelet function, contributing valuable insights into thromboxane signaling pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 85505-64-2
Applications Thromboxane A2 Receptor Antagonist
Formula C30H39NO4
Molecular Weight 477.63
Synonyms GR 32191
SMILES
OC(CC/C=C\CC[C@@H]1[C@@H](N2CCCCC2)[C@H](C[C@@H]1OCC3=CC=C(C4=CC=CC=C4)C=C3)O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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