• Sign In
  • FAQ
  • Create an Account
Currency
USD currency flagUSD
Toggle Nav
My Cart
Menu
Account
Settings
Currency
USD currency flagUSD

Vapreotide

Catalog No.: A61985
Neurokinin Receptor Antagonist
Vapreotide is a neurokinin-1 (NK1) receptor antagonist, demonstrating an IC50 of 330 nM. It effectively inhibits the binding of substance P to the NK1 receptor, making it a valuable tool in research concerning pain modulation, anxiety, and the regulation of neurogenic inflammation. Vapreotide's applications extend to studies of gastrointestinal disorders and therapeutic strategies for conditions associated with elevated neurokinin levels.
Vapreotide 103222-11-3 Neurokinin Receptor Antagonist
Grouped product items
Size Price Stock Qty
5mg
$65.00
In stock
10mg
$110.00
In stock
25mg
$210.00
In stock
50mg
$330.00
In stock
100mg
$520.00
In stock
Bulk Size
Bulk Discount
Bulk Inquiry
Notify me when the price drops
Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionVapreotide is a neurokinin-1 (NK1) receptor antagonist, demonstrating an IC50 of 330 nM. It effectively inhibits the binding of substance P to the NK1 receptor, making it a valuable tool in research concerning pain modulation, anxiety, and the regulation of neurogenic inflammation. Vapreotide's applications extend to studies of gastrointestinal disorders and therapeutic strategies for conditions associated with elevated neurokinin levels.
Product Information
Catalog NumA61985
FormulaC57H70N12O9S2
Molecular Weight1131.37
CAS Number103222-11-3
Sequence{d-Phe}-Cys-Tyr-{d-Trp}-Lys-Val-Cys-Trp-NH2 (Disulfide bridge: Cys2-Cys7)
Sequence shortening{d-Phe}-CY-{d-Trp}-KVCW-NH2 (Disulfide bridge: Cys2-Cys7)
SMILES[H][C@@]1(Cc2ccc(O)cc2)NC(=O)[C@H](CSSC[C@H](NC(=O)C(NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC1=O)C(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O)NC(=O)[C@H](N)Cc1ccccc1 |@:49|
SynonymsRC160; BMY 41606
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

GPCR/G Protein > Neurokinin Receptors