Fig. 1 · Structure
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(±)-Vasicine ((±)-Peganine)
H+-K+-ATPase Inhibitor
(±)-Vasicine is a potent inhibitor of H+-K+-ATPase, with an observed IC50 of 73.47 μg/mL. This compound exhibits notable anti-ulcer properties, demonstrating significant anti-secretory, antioxidant, and cytoprotective effects. As such, (±)-Vasicine serves as a valuable reagent for research applications focused on gastrointestinal protection and related mechanisms in cellular physiology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 6159-56-4 |
| Applications | H+-K+-ATPase Inhibitor |
| Formula | C11H12N2O |
| Molecular Weight | 188.23 |
| Synonyms | (±)-Peganine |
| SMILES | OC1CCN2C1=NC3=C(C=CC=C3)C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.