vc-PABC-DM1

Catalog No.: A42941
ADC Linker
vc-PABC-DM1 is an antibody-drug conjugate (ADC) linker that incorporates a disulfide bond to facilitate controlled drug release. This compound is instrumental in synthesizing ADCs, allowing for targeted delivery of toxins to cancer cells. Additionally, vc-PABC-DM1 can be utilized in studies assessing serum stability, contributing to the understanding of ADC pharmacokinetics and therapeutic efficacy.
Grouped product items
Size Price Stock Qty
1mg
$290.00
In stock
5mg
$745.00
In stock
10mg
$1,220.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionvc-PABC-DM1 is an antibody-drug conjugate (ADC) linker that incorporates a disulfide bond to facilitate controlled drug release. This compound is instrumental in synthesizing ADCs, allowing for targeted delivery of toxins to cancer cells. Additionally, vc-PABC-DM1 can be utilized in studies assessing serum stability, contributing to the understanding of ADC pharmacokinetics and therapeutic efficacy.
Product Information
Catalog NumA42941
FormulaC53H75ClN8O13S
Molecular Weight1099.73
CAS Number1416792-90-9
SMILESC[C@]12[C@@]([C@@H]([C@]3([H])C[C@]([C@@H](/C=C/C=C(CC4=CC(N(C(C[C@@H]2OC([C@H](C)N(C)C(CCSCC5=CC=C(C=C5)NC([C@H](CCCNC(N)=O)NC([C@@H](N)C(C)C)=O)=O)=O)=O)=O)C)=C(C(OC)=C4)Cl)\C)OC)(NC(O3)=O)O)C)([H])O1
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