Fig. 1 · Structure

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VEC6

Cat. No. A73239 CAS 3431-16-1

Endogenous Metabolite

VEC6 (NSC 11435) is an inhibitor of the VEZF1-DNA interaction, demonstrating significant activity in modulating vascular responses during ischemic retinopathy. It effectively reduces pathological angiogenesis while promoting lymphangiogenesis by influencing the expression of distinct gene sets in endothelial cells. VEC6 inhibits VEZF1-mediated transcriptional activity, thereby impacting endothelial cell proliferation and sprouting. This compound serves as a valuable tool for studying the molecular mechanisms of angiogenesis and lymphangiogenesis in various research applications.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3431-16-1
Applications Endogenous Metabolite
Formula C14H20N4
Molecular Weight 244.34
Synonyms NSC 11435
SMILES
CN(C(CCC1)C2)C1CN2/N=N/C3=CC=CC=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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