VEC6 (NSC 11435) is an inhibitor of the VEZF1-DNA interaction, demonstrating significant activity in modulating vascular responses during ischemic retinopathy. It effectively reduces pathological angiogenesis while promoting lymphangiogenesis by influencing the expression of distinct gene sets in endothelial cells. VEC6 inhibits VEZF1-mediated transcriptional activity, thereby impacting endothelial cell proliferation and sprouting. This compound serves as a valuable tool for studying the molecular mechanisms of angiogenesis and lymphangiogenesis in various research applications.
VEC6 (NSC 11435) is an inhibitor of the VEZF1-DNA interaction, demonstrating significant activity in modulating vascular responses during ischemic retinopathy. It effectively reduces pathological angiogenesis while promoting lymphangiogenesis by influencing the expression of distinct gene sets in endothelial cells. VEC6 inhibits VEZF1-mediated transcriptional activity, thereby impacting endothelial cell proliferation and sprouting. This compound serves as a valuable tool for studying the molecular mechanisms of angiogenesis and lymphangiogenesis in various research applications.
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