Fig. 1 · Structure
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Velnacrine maleate
Cholinesterase Inhibitor
Velnacrine maleate is an orally active cholinesterase inhibitor that targets the enzyme acetylcholinesterase, thus increasing acetylcholine levels in the brain. This compound is primarily utilized in research studying Alzheimer's disease and its associated cognitive decline. Through modulation of cholinergic neurotransmission, Velnacrine maleate provides insights into potential therapeutic strategies for neurological disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 118909-22-1 |
| Applications | Cholinesterase Inhibitor |
| Formula | C17H18N2O5 |
| Molecular Weight | 330.34 |
| Synonyms | HP 029; Hydroxytacrine maleate |
| SMILES | OC(/C=C\C(O)=O)=O.NC1=C2C(CCCC2O)=NC3=CC=CC=C31 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.