Fig. 1 · Structure
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Verucopeptin
v-ATPase Inhibitor
Verucopeptin is a selective v-ATPase inhibitor that targets the ATP6V1G subunit, effectively reducing v-ATPase activity. This compound has a notable impact on HIF-1 signaling, decreasing the expression of HIF-1α and its target genes. Additionally, Verucopeptin demonstrates antitumor properties against multidrug resistant (MDR) cancers, making it a valuable tool for cancer research. Its specific mechanism and biological activity position it as a significant reagent for studies focused on tumor biology and therapy resistance.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 138067-14-8 |
| Applications | v-ATPase Inhibitor |
| Formula | C43H73N7O13 |
| Molecular Weight | 896.08 |
| SMILES | N(C([C@@](C)(O)C1(O)O[C@H](\C(=C\[C@H](C[C@H](C[C@@H](CC)C)C)C)\C)[C@@H](OC)CC1)=O)[C@H]2[C@H](C(C)C)OC(=O)CN(C)C(=O)CNC(=O)CN(C)C(=O)CN(O)C(=O)[C@@]3(N(C2=O)NCCC3)[H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.