Vestipitant mesylate is a selective NK1 receptor antagonist that effectively crosses the blood-brain barrier. With a high affinity for the human NK1 receptor (pKi: 9.65), this compound is instrumental in studying various neuropsychiatric conditions, including depression and anxiety disorders, as well as in investigating its effects on nausea and vomiting. Its oral bioavailability further facilitates its use in in vivo research applications.
Vestipitant mesylate is a selective NK1 receptor antagonist that effectively crosses the blood-brain barrier. With a high affinity for the human NK1 receptor (pKi: 9.65), this compound is instrumental in studying various neuropsychiatric conditions, including depression and anxiety disorders, as well as in investigating its effects on nausea and vomiting. Its oral bioavailability further facilitates its use in in vivo research applications.
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