Fig. 1 · Structure
Documents & Downloads
Vestipitant mesylate
NK1 Receptor Antagonist
Vestipitant mesylate is a selective NK1 receptor antagonist that effectively crosses the blood-brain barrier. With a high affinity for the human NK1 receptor (pKi: 9.65), this compound is instrumental in studying various neuropsychiatric conditions, including depression and anxiety disorders, as well as in investigating its effects on nausea and vomiting. Its oral bioavailability further facilitates its use in in vivo research applications.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 334476-64-1 |
| Applications | NK1 Receptor Antagonist |
| Formula | C24H28F7N3O4S |
| Molecular Weight | 587.55 |
| Synonyms | GW597599 mesylate; GW597599B |
| SMILES | O=C(N1CCNC[C@@H]1C2=CC=C(F)C=C2C)N([C@@H](C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)C)C.CS(=O)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.