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VHR-IN-5

VHR Phosphatase Inhibitor

VHR-IN-5 is a selective inhibitor of vaccinia H1-related phosphatase (VHR) with an IC50 value of 78 nM, demonstrating significant inhibition while exhibiting weaker effects against other phosphatases such as MKP-1 and CD45. This compound effectively inhibits HeLa cell proliferation, making it a valuable tool for investigating cervical cancer mechanisms. Its specificity for VHR highlights its potential for research applications in cancer biology and therapeutic development.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	956442-05-0
Applications	VHR Phosphatase Inhibitor
Formula	C₂₈H₂₃N₃O₅S₃
Molecular Weight	577.69
SMILES	O=C(N(C(S/1)=S)CCS(=O)(O)=O)C1=C\C2=CN(C3=CC=CC=C3)N=C2C4=CC=C(C=C4)OCC5=CC=CC=C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.