Target & Activity
| Target | Activity | Value |
|---|---|---|
| Human DHODH | 134 nM |
Fig. 1 · Structure
Documents & Downloads
Vidofludimus (4SC-101)
Cat. No.
A12997
CAS
717824-30-1
DHODH inhibitor
Vidofludimus is a novel orally active and potent DHODH inhibitor.
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Biological Activity
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 717824-30-1 |
| Applications | DHODH inhibitor |
| Formula | C20H18FNO4 |
| Molecular Weight | 355.36 |
| Synonyms | 4SC 101; SC12267 |
| SMILES | COC1=CC=CC(=C1)C2=CC(=C(C=C2)NC(=O)C3=C(CCC3)C(=O)O)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
| Solvent | Reported Solubility |
|---|---|
| DMSO | Warmed: 96 mg/mL (270.14 mM) |
| Water | Insoluble |
| Ethanol | Warmed: 1 mg/mL (2.81 mM) |
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
In Vivo Preparation
- Concentration
- 19 mg/mL
- Vehicle
- Suspended in water
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.