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Vilobelimab
Vilobelimab (CaCP-29, IFX-1) is a monoclonal antibody specifically targeting C5a, a potent pro-inflammatory peptide derived from the complement system. By binding to C5a, Vilobelimab effectively inhibits its interaction with the C5a receptor, thereby attenuating neutrophil activation and chemotaxis. This inhibition plays a crucial role in reducing inflammatory signaling pathways associated with severe clinical conditions such as organ dysfunction. Vilobelimab is highly relevant for research in pathological states where the complement cascade contributes to disease progression, including sepsis and COVID-19.
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Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2250440-41-4 |
| Molecular Weight | 145880 |
| Synonyms | CaCP-29; IFX-1 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.