Vincristine-d3 sulfate is a deuterium-labeled derivative of Vincristine sulfate, a potent antitumor vinca alkaloid that targets microtubule formation. By inhibiting the assembly of microtubules in the mitotic spindle, it effectively causes cell cycle arrest at the metaphase stage. This compound exhibits a binding affinity to microtubules with a Ki value of 85 nM, making it an important tool for cancer research and studies exploring cell division processes.
Vincristine-d3 sulfate is a deuterium-labeled derivative of Vincristine sulfate, a potent antitumor vinca alkaloid that targets microtubule formation. By inhibiting the assembly of microtubules in the mitotic spindle, it effectively causes cell cycle arrest at the metaphase stage. This compound exhibits a binding affinity to microtubules with a Ki value of 85 nM, making it an important tool for cancer research and studies exploring cell division processes.
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