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Vincristine is a mitotic inhibitor, and is used in cancer chemotherapy.
Targets
| Microtubules (Cell-free assay) | ||||
| 32 μM |
| In vitro (25°C) | DMSO | 100 mg/mL (108.33 mM) | |
| Water | 60 mg/mL (65 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
| In vivo | Saline | 30 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 10.83 mL | 54.17 mL | 108.34 mL |
| 0.5 mM | 2.17 mL | 10.83 mL | 21.67 mL |
| 1 mM | 1.08 mL | 5.42 mL | 10.83 mL |
| 5 mM | 0.22 mL | 1.08 mL | 2.17 mL |
*The above data is based on the productmolecular weight 923.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Technical Details
| Catalog Num | A10973 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 923.0 |
| Formula | C46H56N4O10.H2SO4 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 2068-78-2 |
| Synonyms | Leurocristine, VCR |
| SMILES | CC[[email protected]@]1(C[[email protected]@H]2C[[email protected]@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[[email protected]]78CCN9[[email protected]]7[[email protected]@](C=CC9)([[email protected]]([[email protected]@]([[email protected]@H]8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O |
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