Biological Activity
Vincristine is a mitotic inhibitor, and is used in cancer chemotherapy.
Targets
Microtubules (Cell-free assay) | ||||
32 μM |
In vitro (25°C) | DMSO | 86 mg/mL (93.16 mM) | |
Water | 52 mg/mL (56.33 mM) | ||
Ethanol | Insoluble | ||
In vivo | Saline | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 10.83 mL | 54.17 mL | 108.34 mL |
0.5 mM | 2.17 mL | 10.83 mL | 21.67 mL |
1 mM | 1.08 mL | 5.42 mL | 10.83 mL |
5 mM | 0.22 mL | 1.08 mL | 2.17 mL |
*The above data is based on the productmolecular weight 923.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10973 |
---|---|
Actions | Inhibitor |
CAS No. | 2068-78-2 |
Formula | C46H56N4O10.H2SO4 |
M. Wt | 923.0 |
Purity | >98% |
Synonyms | Leurocristine, VCR |
SMILES | CC[[email protected]@]1(C[[email protected]@H]2C[[email protected]@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[[email protected]]78CCN9[[email protected]]7[[email protected]@](C=CC9)([[email protected]]([[email protected]@]([[email protected]@H]8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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