Fig. 1 · Structure
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VT-105
TEAD Inhibitor
VT-105 is a selective TEAD inhibitor that targets the central hydrophobic pocket of the TEAD3 protein. It exhibits potent inhibitory activity, making it a valuable tool for studying the role of TEAD in cellular processes. This compound is particularly relevant for research applications involving NF2-deficient malignant mesothelioma, contributing to the understanding of tumorigenesis and potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2417718-38-6 |
| Applications | TEAD Inhibitor |
| Formula | C24H18F3N3O |
| Molecular Weight | 421.41 |
| SMILES | C[C@@H](C1=CC=CC=N1)NC(C2=CC3=C(N=C2)C(C4=CC=C(C=C4)C(F)(F)F)=CC=C3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.