VT104

Catalog No.: A44023
YAP/TAZ Inhibitor
VT104 is a potent and orally active inhibitor of the YAP/TAZ signaling pathway. It effectively prevents the palmitoylation of endogenous TEAD1 and TEAD3 proteins, thereby modulating downstream gene expression. This compound is valuable for research applications focused on cancer biology, particularly in studies aimed at understanding the role of YAP/TAZ in oncogenesis and tumor progression.
Grouped product items
Size Price Stock Qty
1mg
$60.00
In stock
5mg
$80.00
In stock
10mg
$135.00
In stock
25mg
$305.00
In stock
50mg
$465.00
In stock
100mg
$630.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionVT104 is a potent and orally active inhibitor of the YAP/TAZ signaling pathway. It effectively prevents the palmitoylation of endogenous TEAD1 and TEAD3 proteins, thereby modulating downstream gene expression. This compound is valuable for research applications focused on cancer biology, particularly in studies aimed at understanding the role of YAP/TAZ in oncogenesis and tumor progression.
Product Information
Catalog NumA44023
FormulaC25H19F3N2O
Molecular Weight420.43
CAS Number2417718-25-1
SMILESO=C(C1=CC=C2C(C3=CC=C(C(F)(F)F)C=C3)=CC=CC2=C1)N[C@H](C4=NC=CC=C4)C
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
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