Fig. 1 · Structure
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VT107
pan-TEAD Auto-Palmitoylation Inhibitor
VT107 is a potent pan-TEAD auto-palmitoylation inhibitor that demonstrates oral bioavailability. By targeting TEAD proteins, VT107 disrupts their palmitoylation, which is crucial for cancer cell proliferation and survival. This compound is applicable in cancer research, particularly in studies focused on modulating TEAD-dependent signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2417718-63-7 |
| Applications | pan-TEAD Auto-Palmitoylation Inhibitor |
| Formula | C25H20F3N3O |
| Molecular Weight | 435.44 |
| SMILES | O=C(C1=CC=C2C(C3=CC=C(C(F)(F)F)C=C3)=CC=CC2=C1)N[C@H](C4=NC(N)=CC=C4)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.