Fig. 1 · Structure
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VU0364572 TFA
M1 Agonist
VU0364572 TFA is a selective allosteric agonist of the M1 muscarinic receptor, exhibiting an EC50 of 0.11 μM. This compound demonstrates neuroprotective properties, making it a potential candidate for mitigating memory impairments and alleviating neuropathology associated with Alzheimer's Disease. Additionally, VU0364572 TFA is capable of penetrating the central nervous system, thus enabling its application in neurological research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1240514-89-9 |
| Applications | M1 Agonist |
| Formula | C23H32F3N3O5 |
| Molecular Weight | 487.51 |
| SMILES | O=C(N1CCC(N2C[C@H](NC(C3=CC=CC=C3C)=O)CCC2)CC1)OCC.O=C(O)C(F)(F)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.