Fig. 1 · Structure
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VU0364572
M1 Agonist
VU0364572 is a selective allosteric agonist of the M1 muscarinic receptor, exhibiting an EC50 of 0.11 μM. It demonstrates neuroprotective effects, making it a valuable tool in investigating memory impairments and neuropathological changes associated with Alzheimer’s Disease. Additionally, VU0364572 is orally bioactive and capable of penetrating the central nervous system, enhancing its utility in neuropharmacological research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1240514-87-7 |
| Applications | M1 Agonist |
| Formula | C21H31N3O3 |
| Molecular Weight | 373.49 |
| SMILES | O=C(N1CCC(N2C[C@H](NC(C3=CC=CC=C3C)=O)CCC2)CC1)OCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.