VU0453379

Catalog No.: A18796

GLP-1R modulator

VU0453379

VU0453379 Chemical Structure

CAS NO. 1638646-27-1

VU0453379 is a CNS-penetrant glucagon-like peptide 1 receptor (GLP-1R) positive allosteric modulator (PAM) with an EC50 of 1.3 μM.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
50 mg
$2,000.00
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Biological Activity

VU0453379 is a CNS-penetrant glucagon-like peptide 1 receptor (GLP-1R) positive allosteric modulator (PAM) with an EC50 of 1.3 μM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.01 mL 115.05 mL 230.11 mL
0.5 mM 4.6 mL 23.01 mL 46.02 mL
1 mM 2.3 mL 11.51 mL 23.01 mL
5 mM 0.46 mL 2.3 mL 4.6 mL

*The above data is based on the productmolecular weight 434.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18796
Actions Modulator
CAS No. 1638646-27-1
Formula C26H34N4O2
M. Wt 434.58
Purity >98%
Synonyms VU0453379; VU-0453379; VU 0453379;
SMILES O=C(C(C1=C2N(C)C3=C1C=CC=C3)=CN(C4CCCC4)C2=O)NC[[email protected]]5N(C(C)C)CCC5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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