VU0455691 is a selective orthosteric antagonist of the M1 muscarinic acetylcholine receptor (mAChR) with a pIC50 of 6.64 and an IC50 of 0.23 µM for human M1. This compound is useful in investigating the physiological and pathological roles of M1 mAChR in various neurological disorders. Its ability to selectively inhibit M1 mAChR activation makes it a valuable tool for research into cholinergic signaling pathways and potential therapeutic interventions.
VU0455691 is a selective orthosteric antagonist of the M1 muscarinic acetylcholine receptor (mAChR) with a pIC50 of 6.64 and an IC50 of 0.23 µM for human M1. This compound is useful in investigating the physiological and pathological roles of M1 mAChR in various neurological disorders. Its ability to selectively inhibit M1 mAChR activation makes it a valuable tool for research into cholinergic signaling pathways and potential therapeutic interventions.
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