Fig. 1 · Structure
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VU6004256
M1 Muscarinic Positive Allosteric Modulator
VU6004256 is a potent and selective positive allosteric modulator of the M1 muscarinic receptor, exhibiting an EC50 value of 155 nM. This compound enhances M1 receptor activity and shows promise in addressing cognitive deficits associated with schizophrenia. It is a valuable tool for research into therapeutic strategies targeting muscarinic receptors in neuropsychiatric disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 2011034-33-4 |
| Applications | M1 Muscarinic Positive Allosteric Modulator |
| Formula | C25H25F2N5O2 |
| Molecular Weight | 465.50 |
| SMILES | O=C(C1=CN(CC2=CC=C(C3=CN(C)N=C3)N=C2)C4=C1C(F)=CC(F)=C4)N[C@@H]5[C@@H](O)CCCC5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.