VU6005806

Catalog No.: A18488
M4 modulator
VU6005806 (AZN-00016130) is a potent muscarnic acethylcholine receptor subtype 4 (M4) positive allosteric modulator (PAM), with EC50s of 94 nM, 28 nM, 87 nM and 68 nM for human, rat, dog and cyno M4, respectively. Used in the research of neuropsychiatric disorders.
Grouped product items
Product Name Price Stock Qty
VU6005806 5mg
$350.00
In stock
VU6005806 10mg
$650.00
In stock
VU6005806 50mg
$2,000.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription VU6005806 (AZN-00016130) is a potent muscarnic acethylcholine receptor subtype 4 (M4) positive allosteric modulator (PAM), with EC50s of 94 nM, 28 nM, 87 nM and 68 nM for human, rat, dog and cyno M4, respectively. Used in the research of neuropsychiatric disorders.
Product Information
Catalog Num A18488
Formula C17H16F3N7O2S
Molecular Weight 439.41
CAS Number 2180914-37-6
SMILES NC1=C(C(NC2CN(C3=NC=C(C(F)(F)F)C=N3)C2)=O)SC4=NN=C(OC)C(C)=C41
Synonyms VU 6005806, VU-6005806, AZN00016130, AZN 00016130
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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