Fig. 1 · Structure
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VU6007496
M1 Positive Allosteric Modulator
VU6007496 is a selective positive allosteric modulator (PAM) of the M1 muscarinic acetylcholine receptor. It enhances receptor activity, contributing to potential improvements in cognitive function and memory processing. Its favorable pharmacokinetics support its use in central nervous system studies and drug discovery related to neurodegenerative diseases. Researchers may explore VU6007496 in preclinical models to investigate its therapeutic effects on cognitive disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 2127101-85-1 |
| Applications | M1 Positive Allosteric Modulator |
| Formula | C25H27N5O2 |
| Molecular Weight | 429.51 |
| SMILES | O=C(NC1CCOCC1)C2=NC(C=CN3C)=C3C(CC4=CC=C(C5=NN(C)C=C5)C=C4)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.