VU6008677 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor, with an EC50 value of 120 nM for hM4. This compound enhances receptor activity and is valuable for studying M4 receptor functions and related signaling pathways. Additionally, VU6008677 demonstrates inhibition of cytochrome P450 and possesses favorable pharmacokinetic properties in rat models, making it suitable for in vivo research applications.
VU6008677 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor, with an EC50 value of 120 nM for hM4. This compound enhances receptor activity and is valuable for studying M4 receptor functions and related signaling pathways. Additionally, VU6008677 demonstrates inhibition of cytochrome P450 and possesses favorable pharmacokinetic properties in rat models, making it suitable for in vivo research applications.
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