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VU6009048

mAChR4 Allosteric Modulator

VU6009048 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor (mAChR4) that exhibits effective central nervous system penetration. This compound is useful for investigating neurological disorders such as Parkinson's disease, Huntington's disease, and schizophrenia, facilitating the exploration of therapeutic options targeting cholinergic signaling pathways. Its mechanism of action enhances receptor activity, making it a valuable tool for research in neuropharmacology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Modulator
CAS Number	2226116-93-2
Applications	mAChR4 Allosteric Modulator
Formula	C₁₆H₁₇N₃S
Molecular Weight	283.39
SMILES	N=1C=CC2=C(SC3=NC(=CC(=C32)C)C)C1NC4CCC4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.