VZ185

Catalog No.: A18685

dual BRD7/9 PROTAC degrader

VZ185

VZ185 Chemical Structure

CAS NO. 2306193-61-1

VZ185 is a potent, fast, and selective dual BRD7/9 PROTAC degrader with DC50s of 4.5 and 1.8 nM, respectively.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
50 mg
$2,000.00
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Biological Activity

VZ185 is a potent, fast, and selective dual BRD7/9 PROTAC degrader with DC50s of 4.5 and 1.8 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.05 mL 50.24 mL 100.48 mL
0.5 mM 2.01 mL 10.05 mL 20.1 mL
1 mM 1 mL 5.02 mL 10.05 mL
5 mM 0.2 mL 1 mL 2.01 mL

*The above data is based on the productmolecular weight 995.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18685
Actions Degrader
CAS No. 2306193-61-1
Formula C53H67FN8O8S
M. Wt 995.21
Purity >98%
Synonyms VZ-185, VZ 185
SMILES O=C([[email protected]]1N(C([[email protected]@H](NC(C2(F)CC2)=O)C(C)(C)C)=O)C[[email protected]](O)C1)NCC3=CC=C(C4=C(C)N=CS4)C=C3OCCCCCN5CCN(CC6=C(OC)C=C(C(C7=CC=NC=C87)=CN(C)C8=O)C=C6OC)CC5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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