WAY 163909 hydrochloride is a selective agonist of the 5-hydroxytryptamine receptor 2C (5-HT2C) with an EC50 of 8 nM and maximum efficacy reaching 90%. Exhibiting minimal interaction with 5-HT2A receptors, it demonstrates a Ki value of 10.5 nM for 5-HT2C, while showing much higher Ki values of 212 nM for 5-HT2A, 343 nM for 5-HT7, and 485 nM for 5-HT2B. This specificity makes it a valuable tool for studying the physiological and pharmacological roles of the 5-HT2C receptor in various biological systems.
WAY 163909 hydrochloride is a selective agonist of the 5-hydroxytryptamine receptor 2C (5-HT2C) with an EC50 of 8 nM and maximum efficacy reaching 90%. Exhibiting minimal interaction with 5-HT2A receptors, it demonstrates a Ki value of 10.5 nM for 5-HT2C, while showing much higher Ki values of 212 nM for 5-HT2A, 343 nM for 5-HT7, and 485 nM for 5-HT2B. This specificity makes it a valuable tool for studying the physiological and pharmacological roles of the 5-HT2C receptor in various biological systems.
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