(±)-WB 4101

Catalog No.: A58354
α1-adrenergic Receptor Antagonist
(±)-WB 4101 is a highly selective antagonist of the α1-adrenergic receptor, effectively inhibiting norepinephrine-induced contraction in vascular smooth muscle. This activity leads to antihypertensive effects and relief of symptoms associated with benign prostatic hyperplasia (BPH). It serves as a valuable tool for research focused on hypertension and BPH, contributing to a deeper understanding of therapeutic strategies in cardiovascular and urological conditions.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(±)-WB 4101 is a highly selective antagonist of the α1-adrenergic receptor, effectively inhibiting norepinephrine-induced contraction in vascular smooth muscle. This activity leads to antihypertensive effects and relief of symptoms associated with benign prostatic hyperplasia (BPH). It serves as a valuable tool for research focused on hypertension and BPH, contributing to a deeper understanding of therapeutic strategies in cardiovascular and urological conditions.
Product Information
Catalog NumA58354
FormulaC19H23NO5
Molecular Weight345.39
CAS Number613-67-2
SMILESCOC1=C(OCCNCC2OC3=CC=CC=C3OC2)C(OC)=CC=C1
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