WEHI-9625

Catalog No.: A18351

tricyclic sulfone inhibitor

WEHI-9625

WEHI-9625 Chemical Structure

CAS NO. N/A

WEHI-9625 is a tricyclic sulfone small molecule inhibitor of apoptosis with an EC50 of 69 nM. WEHI-9625 binds to VDAC2 and promotes its ability to inhibit apoptosis driven by mouse BAK, but is completely inactive against both human BAK and the closely related apoptosis effector BAX.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
50 mg
$2,100.00
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Biological Activity

WEHI-9625 is a tricyclic sulfone small molecule inhibitor of apoptosis with an EC50 of 69 nM. WEHI-9625 binds to VDAC2 and promotes its ability to inhibit apoptosis driven by mouse BAK, but is completely inactive against both human BAK and the closely related apoptosis effector BAX.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.84 mL 84.22 mL 168.43 mL
0.5 mM 3.37 mL 16.84 mL 33.69 mL
1 mM 1.68 mL 8.42 mL 16.84 mL
5 mM 0.34 mL 1.68 mL 3.37 mL

*The above data is based on the productmolecular weight 593.71. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18351
Actions Inhibitor
M. Wt 593.71
Formula C34H27NO5S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. N/A
Synonyms WEHI9625, WEHI 9625
SMILES O=C(C(S1)=CC(CS2(=O)=O)=C1C3=C2C=C(C4=CC=CC=C4C(C5=CC=C(OC)C=C5)=O)C=C3)NCC6=CC=C(C)C=C6

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