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WIN 62577

NK1 Receptor Antagonist

WIN 62577 is a selective antagonist of the tachykinin NK1 receptor, exhibiting significant potency in blocking receptor activity. Additionally, it acts as an allosteric enhancer at M3 receptors with micromolar efficacy. This compound demonstrates potent antiviral properties against SARS-CoV-2, making it a valuable tool for research in virology and receptor signaling pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	138091-43-7
Applications	NK1 Receptor Antagonist
Formula	C₂₉H₃₁N₃O
Molecular Weight	437.58
SMILES	C[C@@]12[C@]3([H])[C@](CCC1=CC4=NC5=NC6=CC=CC=C6N5C=C4C2)([H])[C@@]7([H])[C@](CC3)([C@](O)(CC7)C#C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.