WIN 66306

Catalog No.: A62054
NK1/NK2 Antagonist
WIN 66306 is a cyclic heptapeptide that acts as an antagonist for neurokinin 1 (NK1) and neurokinin 2 (NK2) receptors. This compound exhibits significant antagonistic activity, making it a valuable tool for studies related to pain, inflammation, and various neurological disorders. Its role in modulating neurokinin signaling pathways supports research applications in pharmacology and neuroscience.
Grouped product items
Size Price Stock Qty
25mg
$2,160.00
In stock
50mg
$2,770.00
In stock
100mg
$3,680.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionWIN 66306 is a cyclic heptapeptide that acts as an antagonist for neurokinin 1 (NK1) and neurokinin 2 (NK2) receptors. This compound exhibits significant antagonistic activity, making it a valuable tool for studies related to pain, inflammation, and various neurological disorders. Its role in modulating neurokinin signaling pathways supports research applications in pharmacology and neuroscience.
Product Information
Catalog NumA62054
FormulaC41H52N8O9
Molecular Weight800.90
CAS Number151928-32-4
SequenceCyclo(Gly-Trp-Pro-Gly-Val-Gly-{(βR)-β-OH-3-(3-Me-2-Butenyl)-Tyr})
Sequence shorteningCyclo(GWPGVG-{(βR)-β-OH-3-(3-Me-2-Butenyl)-Tyr})
SMILESCC(C)[C@H](NC(=O)CNC(=O)[C@@H]1CC=CN1C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)C(=O)NCC(=O)N[C@H](C=O)[C@H](O)c1ccc(O)c(CC=C(C)C)c1
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