Fig. 1 · Structure
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WLB-87848
σ1 receptor Agonist
WLB-87848 is a selective σ1 receptor agonist with a Ki value of 9 nM, demonstrating high oral bioavailability and the ability to penetrate the blood-brain barrier. This compound has been shown to effectively rescue recognition memory impairment, making it a valuable tool for research in neurodegenerative diseases and memory-related disorders. Its specific targeting of the σ1 receptor positions WLB-87848 as a promising candidate for further investigation in cognitive enhancement studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 2839205-09-1 |
| Applications | σ1 receptor Agonist |
| Formula | C17H15F2N3OS |
| Molecular Weight | 347.38 |
| SMILES | FC(C=CC([C@H](N1C=NC(SC2=C3CCNC2)=C3C1=O)C)=C4)=C4F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.