Fig. 1 · Structure
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Wortmannin-Rapamycin Conjugate 1
Wortmannin-Rapamycin Conjugate
Wortmannin-Rapamycin Conjugate 1 is a furan ring-opened derivative that targets the PI3K/AKT signaling pathway with potent antitumor activity. Its ability to inhibit AKT phosphorylation makes it a valuable reagent for cancer research. Additionally, this compound exhibits favorable water solubility, enhancing its applicability in various biological assays. Researchers can utilize Wortmannin-Rapamycin Conjugate 1 to investigate mechanisms of tumor growth and therapeutic responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1067892-47-0 |
| Applications | Wortmannin-Rapamycin Conjugate |
| Formula | C88H131N3O23 |
| Molecular Weight | 1598.99 |
| SMILES | C[C@@]12C3=C(C(C(O)=C1/C(C(O[C@@H]2COC)=O)=C\N(C)CCCN(C)C)=O)[C@@]4([H])[C@](C[C@H]3OC(C)=O)([C@H](CC4)OC(CCCCCCC(O[C@H]5[C@@H](C[C@@H](CC5)C[C@H]([C@@]6([H])OC([C@@]7([H])N(CCCC7)C(C([C@@]8(O[C@](CC[C@H]8C)([H])C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@H](C([C@@H]([C@@H](/C(C)=C/[C@H](C(C6)=O)C)O)OC)=O)C)C)OC)O)=O)=O)=O)C)OC)=O)=O)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.