Fig. 1 · Structure

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WR 30090

Antimalarial Agent

WR 30090 is a potent antimalarial agent that functions independently of the classical antifolate pathway. It demonstrates significant efficacy against both chloroquine-sensitive and resistant strains of Plasmodium falciparum, particularly against the highly resistant Vietnamese strain. In preclinical models, WR 30090 exhibits high antimalarial activity with a minimum effective dose of 5 mg/kg and a minimum cure dose of 20 mg/kg, making it a valuable tool for research focused on acute malaria.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 19160-62-4
Applications Antimalarial Agent
Formula C25H28Cl4N2O
Molecular Weight 514.31
SMILES
ClC=1C=C(Cl)C2=NC(=CC(=C2C1)C(O)CN(CCCC)CCCC)C=3C=CC(Cl)=C(Cl)C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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