WR99210 is a effective inhibitor of dihydrofolate reductase (DHFR) with an IC50 of <0.075 nM. WR99210 is effective against the most pyrimethamine-resistant Plasmodium falciparum strains.
WR99210 is a effective inhibitor of dihydrofolate reductase (DHFR) with an IC50 of <0.075 nM. WR99210 is effective against the most pyrimethamine-resistant Plasmodium falciparum strains.
Cell Research
Cell Line
Type
Value
Description
References
Product Information
Catalog Num
A18837
Formula
C14H18Cl3N5O2
Molecular Weight
394.68
CAS Number
47326-86-3
SMILES
CC1(N=C(N=C(N1OCCCOC2=C(C=C(C(Cl)=C2)Cl)Cl)N)N)C
Synonyms
WR 99210, WR-99210
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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