WR99210

Catalog No.: A18837

DHFR inhibitor

WR99210

WR99210 Chemical Structure

CAS NO. 47326-86-3

WR99210 is a effective inhibitor of dihydrofolate reductase (DHFR) with an IC50 of <0.075 nM. WR99210 is effective against the most pyrimethamine-resistant Plasmodium falciparum strains.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
50 mg
$2,000.00
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Biological Activity

WR99210 is a effective inhibitor of dihydrofolate reductase (DHFR) with an IC50 of <0.075 nM. WR99210 is effective against the most pyrimethamine-resistant Plasmodium falciparum strains.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.34 mL 126.68 mL 253.37 mL
0.5 mM 5.07 mL 25.34 mL 50.67 mL
1 mM 2.53 mL 12.67 mL 25.34 mL
5 mM 0.51 mL 2.53 mL 5.07 mL

*The above data is based on the productmolecular weight 394.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18837
Actions Inhibitor
CAS No. 47326-86-3
Formula C14H18Cl3N5O2
M. Wt 394.68
Purity >98%
Synonyms WR 99210, WR-99210
SMILES CC1(N=C(N=C(N1OCCCOC2=C(C=C(C(Cl)=C2)Cl)Cl)N)N)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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