Fig. 1 · Structure
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Wu-5
USP10 inhibitor
Wu-5 is a USP10 inhibitor that disrupts FLT3 and AMPK signaling pathways. It promotes the degradation of FLT3-ITD and induces apoptosis, making it a promising compound for research in FLT3-driven malignancies such as acute myeloid leukemia.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2630378-05-9 |
| Applications | USP10 inhibitor |
| Formula | C15H13NO7S |
| Molecular Weight | 351.33 |
| SMILES | O=C(C1=CC=C(C=C1)OC2=C([N+]([O-])=O)C=C(C(OCC)=O)S2)OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.