WY-50295 is a selective inhibitor of 5-lipoxygenase, impacting the biosynthesis of leukotrienes. It demonstrates an IC50 of 40 μM in inhibiting LTB4 formation in rat whole blood leukocytes, with an oral ED50 of 18 mg/kg. This compound is valuable for studying asthma and other conditions associated with leukotriene signaling.
WY-50295 is a selective inhibitor of 5-lipoxygenase, impacting the biosynthesis of leukotrienes. It demonstrates an IC50 of 40 μM in inhibiting LTB4 formation in rat whole blood leukocytes, with an oral ED50 of 18 mg/kg. This compound is valuable for studying asthma and other conditions associated with leukotriene signaling.
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