Xanthohumol I is a chalcone derivative of Xanthohumol, known for its role as a Cholinesterase (ChE) inhibitor. It effectively inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50 values of 71.34 μM and 32.67 μM, respectively. Additionally, its hydroxy derivative, 3-hydroxy-xanthohumol, also demonstrates inhibitory effects on AChE and BChE, with IC50 values of 51.25 μM and 63.07 μM. This compound is valuable for research in neurodegenerative diseases and related biochemical pathways.
Xanthohumol I is a chalcone derivative of Xanthohumol, known for its role as a Cholinesterase (ChE) inhibitor. It effectively inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50 values of 71.34 μM and 32.67 μM, respectively. Additionally, its hydroxy derivative, 3-hydroxy-xanthohumol, also demonstrates inhibitory effects on AChE and BChE, with IC50 values of 51.25 μM and 63.07 μM. This compound is valuable for research in neurodegenerative diseases and related biochemical pathways.
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