Xanthohumol

Catalog No.: A15919

COX inhibitor

Xanthohumol

Xanthohumol Chemical Structure

CAS NO. 6754-58-1

Xanthohumol, a prenylated chalcone from hop, inhibits COX-1 and COX-2 activity and shows chemopreventive effects.

Availability: In stock

Package Price Qty
5 mg
$75.00
10 mg
$140.00
25 mg
$280.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Xanthohumol, a prenylated chalcone from hop, inhibits COX-1 and COX-2 activity and shows chemopreventive effects.
Targets
COX-1 COX-2
In vitro (25°C) DMSO 67 mg/mL (189.05 mM)
Water Insoluble
Ethanol 67 mg/mL (189.05 mM)
In vivo 0.05% (w+w) xanthohumol powder in diet, or suspended in ethanol (2.5 mg+mL) 12 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.22 mL 141.08 mL 282.17 mL
0.5 mM 5.64 mL 28.22 mL 56.43 mL
1 mM 2.82 mL 14.11 mL 28.22 mL
5 mM 0.56 mL 2.82 mL 5.64 mL

*The above data is based on the productmolecular weight 354.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15919
Actions Inhibitor
CAS No. 6754-58-1
Formula C21H22O5
M. Wt 354.4
Purity >98%
SMILES CC(=CCC1=C(C=C(C(=C1O)C(=O)C=CC2=CC=C(C=C2)O)OC)O)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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