Fig. 1 · Structure

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XH161-180

USP2 Inhibitor

XH161-180 is a potent and orally bioavailable inhibitor of ubiquitin-specific protease 2 (USP2). This compound effectively decreases levels of cyclin D and ACE2, demonstrating significant antiproliferative activity. XH161-180 is valuable for research applications related to cancer biology and viral infections associated with ACE2 modulation.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3058588-52-3
Applications USP2 Inhibitor
Formula C22H21BrFN3O3S2
Molecular Weight 538.45
SMILES
O=C(NC1=NC(C2=CC=C(Br)C=C2)=CS1)C3=CC=C(F)C=C3NS(=O)(C4CCCCC4)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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