Fig. 1 · Structure
Documents & Downloads
XO44
Kinase Probe
XO44 is a broad-spectrum covalent kinase probe that primarily targets cyclin-dependent kinases, including CDK1, CDK2, and CDK4. This compound is instrumental in the study of cell cycle regulation and kinase signaling pathways, providing valuable insights into cancer research and therapeutics. Its ability to label CDK proteins in cellular contexts enhances its utility in probing kinase activity and interactions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2088112-70-1 |
| Applications | Kinase Probe |
| Formula | C25H27FN8O3S |
| Molecular Weight | 538.60 |
| Synonyms | PF-6808472 |
| SMILES | O=S(C1=CC=C(CN2CCN(C3=NC(C(NCC#C)=O)=CC(NC4=NNC(C5CC5)=C4)=N3)CC2)C=C1)(F)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.