Fig. 1 · Structure

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XSJ2-46

Antiviral Agent

XSJ2-46 is a 5'-amino NI analog that functions as an antiviral agent targeting RNA-dependent RNA polymerases (RdRp). It demonstrates significant anti-Zika virus activity, with an IC50 value of 8.78 μM, indicating its potential as a therapeutic candidate in viral research. This compound is suitable for studies focused on elucidating the mechanisms of Zika virus replication and developing antiviral strategies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2265911-12-2
Applications Antiviral Agent
Formula C25H24ClF3N6O3
Molecular Weight 548.94
SMILES
O[C@H]1[C@@H](O)[C@H](N2C3=C(N=C2)C(NCC4=CC(Cl)=CC=C4)=NC=N3)O[C@@H]1CNCC5=CC=C(C(F)(F)F)C=C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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