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YJ182

NDM-1 Inhibitor

YJ182 is a selective NDM-1 inhibitor with an IC50 of 0.23 μM. It also demonstrates inhibitory activity against IMP-1, VIM-2, GIM-1, and MMP-2, with IC50 values of 0.25, 0.61, 0.49, and 6.92 μM, respectively. This compound is valuable for research focused on bacterial infections and the development of resistance mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3035446-91-1
Applications	NDM-1 Inhibitor
Formula	C₂₁H₁₅N₃O₄S
Molecular Weight	405.43
SMILES	O=C(O)C1=NC2=C(NS(=O)(C3=CC=CC=N3)=O)C=CC=C2C(C4=CC=CC=C4)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.